海南醫(yī)學院海南省熱帶病重點實驗室導師：黃燦華

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海南醫(yī)學院海南省熱帶病重點實驗室導師：黃燦華正文

[導師姓名]
黃燦華

[所屬院校]
海南醫(yī)學院

[基本信息]
導師姓名：黃燦華
性別：男
人氣指數(shù)：1514
所屬院校：海南醫(yī)學院
所屬院系：海南省熱帶病重點實驗室
職稱：
導師類型：
招生專業(yè)：病理學與病理生理學
研究領域：腫瘤發(fā)生和干預

[通訊方式]
辦公電話：13258370346
電子郵件：hcanhua@hotmail.com

[個人簡述]
2000年在中國科學院獲博士學位，隨后在新加坡國立大學生物系從事博士后研究。2003 年8月被新加坡國立大學腫瘤研究所聘為Research Scientist。2005年9月回國任四川大學生物治療國家重點實驗室教授。國家杰出青年科學基金獲得者（2012）；國家重大科學研究計劃（973計劃） “病毒誘導腫瘤發(fā)生的氧化還原蛋白質組研究”項目首席科學家(2013-2017)；教育部長江學者特聘教授（2013、2014）。中國生物化學與分子生物學會蛋白質組學專業(yè)委員會委員；國際學術刊物　Proteomics、 Signal Transduction and Targeted Therapy 編委委員。
回國以來以通訊作者在　Mol Cell Proteomics (5篇)、Gastroenterology、Cancer Res (封面論文)、Autophagy (3篇)、Cell Death Differ、 Oncotarget、J Cell Sci、J Infect Dis、Carcinogenesis、J Biol Chem 等學術刊物上發(fā)表SCI論文50余篇，其中30篇論文影響因子大于5.0，被引用1400余次。受邀請在　Mass Spectrom Rev、Med Res Rev、Expert Rev Proteomics (5篇) 等國際學術刊物上發(fā)表多篇關于系統(tǒng)生物學前沿綜述；作為客座編輯出版一期　Comb Chem High Throughput Screen (2012)。受邀請在“The 2nd Proteomics Symposium on Inflammation and Cancer”(2014/05 廣州)、“Asia Oceania Human Proteome Organization (AOHUPO) 8th Congress”(2013/09 重慶)、“The 18th Annual Lorne Proteomics Symposium”(2013/02 Lorne, Australia)、“CSH Asia/ICMS腫瘤微環(huán)境聯(lián)合會議”(2012/11 蘇州)、“Asia Oceania Human Proteome Organization (AOHUPO) 6th Congress”(2012/05 北京)、“第一屆自噬生物學與疾病國際研討會”(2015/06 北京)做大會特邀(主題)報告。

[科研工作]
1. Yuan K, Lei Y, Chen H, Chen Y, Zhang T, Li K, Xie N, Wang K, Feng X, Pu Q, Yang W, Wu Min, Xiang R, Feitelson MA, Nice EC, Wei Y, Huang C*. HBV-induced ROS accumulation promotes hepatocarcinogenesis through Snail-mediated epigenetic silencing of SOCS3. Cell Death Differ. (In press) (IF=8.184)
2. Zhang L, Wang K, Lei Y, Li Q, Nice EC, Huang C*. Redox Signaling: Potential Arbitrator of Autophagy and Apoptosis in Therapeutic Response. Free Radical Bio Med. (In press) (IF=5.736)
3. Liu R, Huang S, Lei Y, Zhang T, Wang K, Liu B, Nice EC, Xiang R, Xie K, Li J*, Huang C*. FGF8 promotes colorectal cancer growth and metastasis by activating YAP1. Oncotarget. 2015 Jan 206(2):935-52. (IF=6.359)
4. Lei Y, Wang K, Deng L, Chen Y, Nice EC, Huang C*. Redox Regulation of Inflammation: Old Elements, a New Story. Med Res Rev. 2015 Mar35(2):306-40. (IF=8.431)
5. Liu R, Li J, Zhang T, Zou L, Chen Y, Wang K, Lei Y, Yuan K, Li Y, Lan J, Cheng L, Xie N, Xiang R, Nice EC, Huang C*, Wei Y. Itraconazole suppresses the growth of glioblastoma through induction of autophagy: Involvement of abnormal cholesterol trafficking. Autophagy. 2014 May 1510(7) (IF=11.753)
6. Liu R, Li J, Xie K, Zhang T, Lei Y, Chen Y, Zhang L, Huang K, Wang K, Wu H, Wu M, Nice EC, Huang C*, Wei Y. FGFR4 promotes stroma-induced epithelial-to-mesenchymal transition in colorectal cancer. Cancer Res. 2013 Oct 173(19):5926-35. (IF=9.329)
7. Wen X, Wu J, Wang F, Liu B*, Huang C*, Wei Y. Deconvoluting the role of reactive oxygen species and autophagy in human diseases. Free Radic Biol Med. 2013 Dec65:402-10. (IF=5.736)
8. Liu R, Huang L, Li J, Zhou X, Zhang H, Zhang T, Lei Y, Wang K, Xie N, Zheng Y, Wang F, Nice EC, Rong L, Huang C*, Wei Y. HIV Infection in gastric epithelial cells. J Infect Dis. 2013 Oct 15208(8):1221-30. (IF=5.997)
9. Wu J, Xie N, Xie K, Zeng J, Cheng L, Lei Y, Liu Y, Song L, Dong D, Chen Y, Zeng R, Nice EC, Huang C*, Wei Y. GPR48, a poor prognostic factor, promotes tumor metastasis and activates β-catenin/TCF signaling in colorectal cancer. Carcinogenesis. 2013 Dec34(12):2861-9. (IF=5.334)
10. Yuan K, Xie K, Fox J, Zeng H, Gao H, Huang C*, Wu M*. Decreased levels of miR-224 and the passenger strand of miR-221 increase MBD2, suppressing maspin and promoting colorectal tumor growth and metastasis in mice. Gastroenterology. 2013 Oct145(4):853-64.e9. (IF=16.716)
11. Deng L, Lei Y, Liu R, Li J, Yuan K, Li Y, Chen Y, Liu Y, Lu Y, Edwards CK 3rd, Huang C*, Wei Y. Pyrvinium targets autophagy addiction to promote cancer cell death. Cell Death Dis. 2013 May 24:e614. (IF=5.014)
12. Wang K, Zhang T, Dong Q, Nice EC, Huang C*, Wei Y. Redox homeostasis: the linchpin in stem cell self-renewal and differentiation. Cell Death Dis. 2013 Mar 144:e537. (IF=5.014)
13. Zhou S, Liu R, Yuan K, Yi T, Zhao X*, Huang C*, Wei Y. Proteomics analysis of tumor microenvironment: Implications of metabolic and oxidative stresses in tumorigenesis. Mass Spectrom Rev. 2013 Jul-Aug32(4):267-311. (IF=7.709)
14. Klionsky DJ, Abdalla FC...Canhua H, et al., Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr8(4):445-44. (IF=11.753)
15. Zhou S, Yi T, Liu R, Bian C, Qi X, He X, Wang K, Li J, Zhao X*, Huang C*, Wei Y. Proteomics identification of annexin A2 as a key mediator in the metastasis and proangiogenesis of endometrial cells in human adenomyosis. Mol Cell Proteomics. 2012 Jul11(7):M112.017988. (IF=6.564)
16. Yuan K, Huang C*, Fox J, Laturnus D, Carlson E, Zhang B, Yin Q, Gao H, Wu M*. Autophagy plays an essential role in the clearance of Pseudomonas aeruginosa by alveolar macrophages. J Cell Sci. 2012 Jan 15125(Pt 2):507-15. (IF=5.432)
17. Zhou S, Li Y, Huang F, Zhang B, Yi T, Li Z, Luo H, He X, Zhong Q, Bian C, Lin X, Qi X, Liu P, Huang C, Zhao X*, Wei Y. Live-attenuated measles virus vaccine confers cell contact loss and apoptosis of ovarian cancer cells via ROS-induced silencing of E-cadherin by methylation. Cancer Lett. 2012 May 1318(1):14-25. (IF=5.621)
18. Lei Y, Huang K, Gao C, Lau QC, Pan H, Xie K, Li J, Liu R, Zhang T, Xie N, Nai HS, Wu H, Dong Q, Zhao X, Nice EC, Huang C*, Wei Y. Proteomics identification of ITGB3 as a key regulator in reactive oxygen species-induced migration and invasion of colorectal cancer cells. Mol Cell Proteomics. 2011 Oct10(10):M110.005397. (IF=6.564)
19. Wang K, Liu R, Li J, Mao J, Lei Y, Wu J, Zeng J, Zhang T, Wu H, Chen L, Huang C*, Wei Y. Quercetin induces protective autophagy in gastric cancer cells: involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling. Autophagy. 2011 Sep7(9):966-78. (IF=11.753)
20. Li J, Liu R, Lei Y, Wang K, Lau QC, Xie N, Zhou S, Nie C, Chen L, Wei Y, Huang C*. Proteomic analysis revealed association of aberrant ROS signaling with suberoylanilide hydroxamic acid-induced autophagy in Jurkat T-leukemia cells. Autophagy. 2010 Aug6(6):711-24. (IF=11.753)
21. Li Z, Huang C*, Bai S, Pan X, Zhou R, Wei Y, Zhao X*. Prognostic evaluation of epidermal fatty acid-binding protein and calcyphosine, two proteins implicated in endometrial cancer using a proteomic approach. Int J Cancer. 2008 Nov 15123(10):2377-83. (IF=5.085)
22. Liu R, Li Z, Bai S, Zhang H, Tang M, Lei Y, Chen L, Liang S, Zhao YL, Wei Y, Huang C*. Mechanism of cancer cell adaptation to metabolic stress: proteomics identification of a novel thyroid hormone-mediated gastric carcinogenic signaling pathway. Mol Cell Proteomics. 2009 Jan8(1):70-85. (IF=6.564)
23. Wang Z, Jiang L, Huang C*, Li Z, Chen L, Gou L, Chen P, Tong A, Tang M, Gao F, Shen J, Zhang Y, Bai J, Zhou M, Miao D, Chen Q*. Comparative proteomics approach to screening of potential diagnostic and therapeutic targets for oral squamous cell carcinoma. Mol Cell Proteomics. 2008 Sep7(9):1639-50. (IF=6.564)
24. Li Z, Zhao X*, Bai S, Wang Z, Chen L, Wei Y, Huang C*. Proteomics identification of cyclophilin a as a potential prognostic factor and therapeutic target in endometrial carcinoma. Mol Cell Proteomics. 2008 Oct7(10):1810-23. (IF=6.564)

[教育背景]
1997-2000 中國科學院武漢病毒研究所/中科院水生生物研究所聯(lián)合培養(yǎng) 研究生/理學博士
1993-1996 中國科學院武漢病毒研究所研究生/理學碩士
1987-1991 湖北大學生物系本科/理學學士 以上老師的信息來源于學校網(wǎng)站，如有更新或錯誤，請聯(lián)系我們進行更新或刪除，聯(lián)系方式

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