沈陽藥科大學(xué)制藥工程學(xué)院導(dǎo)師：胡春 正文

[導(dǎo)師姓名]
胡春

[所屬院校]
沈陽藥科大學(xué)

[基本信息]
導(dǎo)師姓名：胡春
性別：男
人氣指數(shù)：1525
所屬院校：沈陽藥科大學(xué)
所屬院系：制藥工程學(xué)院
職稱：教授
導(dǎo)師類型：碩導(dǎo)/博導(dǎo)
招生專業(yè)：有機(jī)化學(xué)、應(yīng)用化學(xué)、藥物化學(xué)、藥學(xué)（藥物化學(xué)方向）
研究領(lǐng)域：研究方向一：雜環(huán)化合物的合成及生物活性研究;研究方向二：醫(yī)藥中間體的研究;研究方向三：金屬...

[通訊方式]
辦公電話：024-43520246
電子郵件：chunhu1999@163.com
通訊地址：沈陽市沈河區(qū)文化路103號

[個(gè)人簡述]
胡春，男，博士，教授。1985年畢業(yè)于江蘇師范大學(xué)，獲化學(xué)學(xué)士學(xué)位，1988年畢業(yè)于東北師范大學(xué)，獲有機(jī)化學(xué)碩士學(xué)位，1999年畢業(yè)于沈陽藥科大學(xué)，獲藥物化學(xué)博士學(xué)位，2014年在香港中文大學(xué)作為高級訪問學(xué)者進(jìn)修一年。1988年起在沈陽藥科大學(xué)工作至今，1995被評為沈陽藥科大學(xué)副教授，2000年晉升為教授，2002年被評為博士生導(dǎo)師。目前的主要研究方向有新藥設(shè)計(jì)與合成、醫(yī)藥中間體的研究、雜環(huán)化合物的合成及生物活性研究、金屬有機(jī)化合物的合成及生物活性研究等。作為課題負(fù)責(zé)人完成了國家自然科學(xué)基金項(xiàng)目3項(xiàng)，國家新藥研究基金2項(xiàng)，國家重大科技專項(xiàng)1項(xiàng)。目前已在ARKIVOC, MedicinalChemistry, Heterocycles, Bioorganic & Medicinal Chemistry Letters, ChemicalResearch in Chinese Universities, Letters in Drug Design & Discovery,Chemico-Biological Interactions, Chinese Chemical Letters, Latin AmericanJournal of Pharmacy, Molecules等期刊發(fā)表論文100余篇，其中SCI收載30余篇。

[科研工作]
近年來發(fā)表代表性論文
1.ZHANG Lan, DENG Xinshan, WU Jiaofeng, MENGGuangpeng, LIU Congchong, CHEN Guzhou, ZHAO Qingchun, HU Chun*. Design,Synthesis and Biological Activities ofN-(Furan-2-ylmethyl)-1H-indole-3-carboxamide Derivatives as Epidemal GrowthFactor Receptor Inhibitors and Anticancer Agents. Chemical Research in ChineseUniversities, 2017, 33(3): 365-372.2.Lan Zhang, Xin-Shan Deng, Chao Zhang, Guang-PengMeng, Jiao-Feng Wu, Xue-Song Li, Qing-Chun Zhao, Chun Hu*. Design, synthesisand cytotoxic evaluation of a novel series of benzo[d]thiazole-2-carboxamidederivatives as potential EGFR inhibitors. Medicinal Chemistry Research, 2017,26(9):2180-2189.3.Wenjing Ye, Xiao Xiao, Lan Wang, Shicheng Hou,Chun Hu*. Synthesis of mono- and binuclear Cu(ii) complexes bearingunsymmetrical bipyridine–pyrazole–amine ligand and their applications inazide–alkyne cycloaddition. Organometallics, 2017, 36 (11): 2116–2125.4.Bing SUN, Jin ZHANG , Xiu’e YIN, Yue XU, FurongZHANG, Yushu HUANG, Jinhui WANG, Guoqing WANG & Chun HU*. Synthesis,Characterization and Biological Activity of thieno[2,3-d]pyrimidine Derivativesas the Epidermal Growth Factor Receptor Inhibitors. Latin American Journal ofPharmacy, 2016, 35(3): 570-577.5.LI Han-Yue, HAN Yu, JIN Zhe, WANG Shi-Hui, LIXin-Zeng, LIU Si-Yu, HU Chun*. The Crystal Structure of3-(4-methoxyphenyl)-2-(4-methylbenzoyl)-6,7-dihydro-5H-furo[3,2-g]chromene.Chinese Journal of Structural Chemistry, 2016, 35(4): 545-549.6.Gang Li, Liang Zhao, Peng Yang, Zhaozheng Yang,Zhangmin Tian, Yan Chen, Hongyan Shen, and Chun Hu*. Engineering 1,3-AlternateCalixcarbazole for Recognition and Sensing of Bisphenol F in Water. Anal Chem.2016 , 88(21):10751-10756.7.Xiao-ping Liu, Hui-lan Xu, Rui Sun, Xue Li,Bao-hua Hu, Chun Hu*. Synthesis and Characterization of Two Impurities inEsomeprazole, an Antiulcerative Drug. Latin American Journal of Pharmacy, 2015,34(6): 1265–1268.8.Bing Sun, Xiu’e Yin, Jin Zhang, Jian Huang, YueXu, Furong Zhang, Jinhui Wang, Guoqing qing Wang, Chun Hu*. Synthesis,Characterization and Biological Activity ofTetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine Derivatives as Epidermal GrowthFactor Receptor Inhibitors. Chemical Research in Chinese Universities, 2015,31(6): 936-941.9.Jianshu Hu, Wei Zhu, Hu Meng, Ying Liu, Xin Wangand Chun Hu*. Identification of 1, 4-Dihydrothieno[3′, 2′:5, 6]thiopyrano[4, 3-c]pyrazole Derivatives asHuman 5-Lipo-oxygenase Inhibitors. Chemical Biology and Drug Design, 2014,84(6): 642–647.10.Xin Wang, Rui Sun, Yushu Huang, Yisi Yan,Miaomiao Gao, Danni Wang, Diwa Koirala, Dawei Li, Chun Hu*. Development ofThieno[3',2':5,6]thiopyrano[4,3-c]pyrazole-3-carboxamide Derivatives as theEstrogen Receptor Ligands: Synthesis, Characterization and Biological Activity.Medicinal Chemistry, 2014, 10(8): 836-942.

[教育背景]

沈陽藥科大學(xué)

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