沈陽藥科大學(xué)制藥工程學(xué)院導(dǎo)師：關(guān)奇 正文

[導(dǎo)師姓名]
關(guān)奇

[所屬院校]
沈陽藥科大學(xué)

[基本信息]
導(dǎo)師姓名：關(guān)奇
性別：男
人氣指數(shù)：1272
所屬院校：沈陽藥科大學(xué)
所屬院系：制藥工程學(xué)院
職稱：講師
導(dǎo)師類型：碩導(dǎo)
招生專業(yè)：藥物化學(xué)
研究領(lǐng)域：研究方向一：抗腫瘤及抗痛風(fēng)創(chuàng)新藥物研究;研究方向二：綠色化學(xué)合成方法研究及生物活性分子的新...

[通訊方式]
電子郵件：guanqi0411@sina.com

[個(gè)人簡述]
關(guān)奇，男，博士，副教授。2010年畢業(yè)于沈陽藥科大學(xué)，獲制藥工程學(xué)士學(xué)位，2015年于同校獲藥物化學(xué)博士學(xué)位。2017年被聘為沈陽藥科大學(xué)副教授。作為課題負(fù)責(zé)人主持了國家自然科學(xué)基金青年基金項(xiàng)目1項(xiàng)、遼寧省科技廳項(xiàng)目1項(xiàng)、遼寧省教育廳項(xiàng)目1項(xiàng)、沈陽市科技計(jì)劃項(xiàng)目1項(xiàng)；另外，作為項(xiàng)目骨干成員承擔(dān)國家自然科學(xué)基金應(yīng)急項(xiàng)目1項(xiàng)。目前已在Green.Chem., Cancer. Lett., Eur. J. Med. Chem., MedChemComm, Bioorg. Med. Chem.Lett., 等期刊發(fā)表論文10余篇。

[科研工作]
近年來發(fā)表代表性論文
1.QiGuan,Mingyang Jiang, Junhui Wu, Yan peng Zhai, Yue Wu, Kai Bao*, Weige Zhang*.Direct cycle between co-product and reactant: an approach to improve the atomeconomy and its application in the synthesis and protection of primary amines.Green chemistry. 18(2016) 5794-5799. (IF=9.125)2.Qi Guan, Chunming Han, Daiying Zuo, Min’an Zhai,Zengqiang Li, Qian Zhang, Yanpeng Zhai, Xuewei Jiang, Kai Bao, Yingliang Wu*, WeigeZhang*. Synthesis andEvaluation of Benzimidazole Carbamates Bearing Indole Moieties forAntiproliferative and Antitubulin Activities. EuropeanJournal of Medicinal Chemistry. 2014, 87, 306-315 (IF=4.519)3.Qi Guan, Fushan Yang, Dandan Guo, Jingwen Xu,Mingyang Jiang, Chunjiang Liu, Kai Bao, Yingliang Wu*, Weige Zhang*. Synthesis and Biological Evaluation of Novel3,4-Diaryl-1,2,5-selenadiazol Analogues of Combretastatin A-4. EuropeanJournal of Medicinal Chemistry. 2014, 87, 1-9 (IF=4.519)4.Qi Guan, Zengjin Cheng, Xiaoxue Ma, Lijie Wang,Dongjie Feng, Yuanhang Cui, Kai Bao, Lan Wu*, Weige Zhang*. Synthesis andBioevaluation of 2-Phenyl-4-methyl- 1,3-selenazole-5-carboxylic Acids as PotentXanthine Oxidase Inhibitors.EuropeanJournal of Medicinal Chemistry. 2014, 85, 508-516 (IF=4.519)5.Qi Guan, Daiying Zuo, NanJiang, Huan Qi, Yanpeng Zhai, Zhaoshi Bai, Dongjie Feng, Lei Yang, MingyangJiang, Kai Bao, Chang Li, Yingliang Wu*, Weige Zhang*.Microwave-assisted Synthesis and BiologicalEvaluation of 3,4-Diaryl Maleic Anhydride/N-Substituted Maleimide Derivativesas Combretastatin A-4 Analogues. Bioorganic & MedicinalChemistry Letters. 2015, 25(3), 631-634 (IF=2.454)6.Qi Guan1, Dongjie Feng1, Zhaoshi Bai,Yuanhang Cui, Daiying Zuo, Min’an Zhai, Xuewei Jiang, Wenbo Zhou, Kai Bao, Yingliang Wu*, Weige Zhang*. Microwave-assisted Synthesis, MolecularDocking and Antiproliferative Activity of3/5-Aryl-5/3-(3,4,5-trimethoxybenzoyl)-1,2,4-oxadiazol Derivatives.Medicinal Chemistry Communications. 2015,6(8), 1484-1493 (IF=2.608)7.AilongShi, Defa Wang, He Wang, Yue Wu, Haiqiu Tian, Qi Guan*, Kai Bao*,Weige Zhang*. Synthesis and bioevaluation of 2-phenyl-5-methyl-2H-1,2,3-triazole-4-carboxylicacid/carbohydrazide derivatives as potent xanthine oxidase inhibitors.RSCAdvances. 6 (2016) 114879-114888. (IF=3.108)

[教育背景]

沈陽藥科大學(xué)

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