周洪 ，男，博士，現(xiàn)為南京醫(yī)科大學(xué)微生物免疫學(xué)系教授，江蘇省特聘教授，生殖醫(yī)學(xué)國(guó)家重點(diǎn)實(shí)驗(yàn)室PI，江蘇省免疫學(xué)會(huì)理事，中國(guó)免疫學(xué)會(huì)青年工作委 員會(huì)委員，J．Immunol.，J．Neuroimmunol.等期刊審稿人。1996年始在上海交通大學(xué)醫(yī)學(xué)院從事免疫調(diào)節(jié)和移植免疫學(xué)研究，自2002年開(kāi)始在北美多個(gè)研究機(jī)構(gòu)一直從事 炎癥和細(xì)胞招募相關(guān)的科研工作，曾獲得加拿大健康研究所獎(jiǎng)學(xué)金。工作主要揭示了小膠質(zhì)細(xì)胞在腦部炎癥狀態(tài)下激活并介導(dǎo)免疫細(xì)胞招募和內(nèi)皮細(xì)胞在系統(tǒng)性炎癥 中通過(guò)TLR4直接識(shí)別病原的具體機(jī)制。2010年11月回國(guó)工作，現(xiàn)主持國(guó)家自然科學(xué)基金，江蘇省自然科學(xué)基金，江蘇省教育廳特聘教授研究基金，國(guó)家重 點(diǎn)實(shí)驗(yàn)室開(kāi)放課題等多項(xiàng)科研項(xiàng)目。

發(fā)表論文：
1．Moriarty, T.J., Shi M, Lin YP, Ebady R, Zhou H, Benoit V., Wu J., Hardy P.O., Salman A．D., Kubes P., Skare J.T., Leong J.M., and Chaconas G．Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules．Mol Microbiol．2012 Oct 24．[Epub ahead of print]
2．Chi J, Hu WX, Gu B, Zhang C, Peng GY, Zhou F, Chen Y, Zhang GF, Guo YD, Guo D, Qin J, Wang JF, Li LL, Wang F, Liu G, Xie F, Feng DJ, Zhou H, Huang X, Lu S, Yao K Human herpesvirus 6 latent infection in glioma patients．J Infect Dis．2012 Sep 7．[Epub ahead of print]
3．Langer HF, Choi EY, Zhou H, Schleicher R, Chung KJ, Tang Z, G?bel K, Bdeir K, Chatzigeorgiou A, Wong C, Bhatia S, Kruhlak MJ, Rose JW, Burns JB, Hill KE, Qu H, Zhang Y, Lehrmann E, Becker KG, Wang Y, Simon DI, Nieswandt B, Lambris JD, Li X, Meuth SG, Kubes P, Chavakis T．Platelets Contribute to the Pathogenesis of Experimental Autoimmune Encephalomyelitis．Circ Res．2012 Mar 28．[Epub ahead of print]
4．Cao J, Song W, Gu B, Mei YL, Tang JP, Meng L, Yang CQ, Wang HJ, Zhou H Correlation between carbapenem consumption and antimicrobial resistance rates of Acinetobacter baumannii in a university affiliated hospital．J Clin Pharmacol．2012 Feb 2．[Epub ahead of print]
5．Shi M, Li S, Zheng C, Jones GJ, Zhou H, Kubes P, Mody CH Real-time imaging of trapping and ureasedependent transmigration of Cryptococcus neoformans in mouse brain．J Clin．Invest．2010, 120: 1683-1693.
6．Lee WY, Moriarty TJ, Wong CH, Zhou H, Chaconas G, Strieter R, Kubes P An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells．Nat Immunol．2010, 11:295-302.
7．Zhou H, Andonegui G, Wong CH, Kubes P Role of endothelial TLR4 for neutrophil recruitment into central nervous system microvessels in systemic inflammation．J Immunol．2009, 183: 5244-5250.
8．Andonegui G*, Zhou H*, Bullard D, Kelly M, MacDonald B, Mullaly S, Long E, Robbins S, Kubes P Mice that exclusively express TLR4 on endothelial cells can efficiently clear a lethal systemic Gram-negative bacterial infection．J Clin Invest．2009, 119: 1921-1930．Research highlighted in Nat Rev Immunol．Aug．2009, 9:532
* Co-first authors equally contributed to the work
9．Menezes G, Lee WY, Zhou H, Waterhouse C, Cara D, Kubes P Selective down-regulation of neutrophil Mac-1 in endotoxemic hepatic microcirculation via IL-10．J Immunol．2009, 183: 7557–7568.
10．Audoy JR, Soulet D, Zhou H, Kubes P, Vallières L Rod-shaped monocytes patrol the brain vasculature and give rise to perivascular macrophages under the influence of pro- inflammatory cytokines and angiopoietin-2．J Neurosci．2008, 28: 10187-10199
11．Zhou H, Lapointe BM, Clark SR, Kubes P．A requirement for microglial TLR4 in leukocyte recruitment into brain in response to LPS．J Immunol．2006, 177:8103-10.
12．Zhou H, Jiao Z, Pan J, Hong J, Tao J, Li N, Zhou Y, Zhang J, Zhou GY．Immune suppression via IL-4/IL-10-secreting T cells: A nontoxic property of anti-HIV agent trichosanthin．Clin Immunol．2007, 122: 312-322.
13．Cao Y, Zhou H, Tao J, Zheng Z, Li N, Shen B, Shih TS, Hong J, Zhang J, Zhou GY．Keratinocytes induce local tolerance to skin graft by activating IL-10-secreting T cells in the context of costimulation molecule B7-H1．Transplantation 2003, 75: 1390-6.

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